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Published on: February 9, 2011
Surgical aspects of bacterial infection in African children
Emmanuel A Ameh1, Francis A Abantanga, Doreen Birabwa-Male
1Division of Paediatric Surgery, Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. eaameh@yahoo.co.uk
Insights
Surgical site infections (SSIs) are common in African children, often exceeding 20% due to poor infection control. Complications and high mortality rates underscore the urgent need for improved surgical infection management in the region.
Area of Science:
- Pediatric Surgery
- Infectious Diseases
- Global Health
Background:
- Surgical site infections (SSIs) are highly prevalent in African children, with rates surpassing 20% even in clean procedures.
- Inadequate infection control and surveillance policies contribute significantly to high SSI rates in African hospitals.
- Typhoid intestinal perforation and complicated appendicitis are major pediatric surgical emergencies in Africa, often presenting late with severe outcomes.
Purpose of the Study:
- To highlight the significant burden of surgical infections in African children.
- To discuss the challenges and current management of common surgical infections like SSIs, typhoid perforation, and appendicitis.
- To underscore the need for enhanced infection control and surveillance strategies.
Main Methods:
- Review of common surgical infections in African pediatric populations.
- Discussion of current surgical interventions and their associated complication rates.
- Analysis of factors contributing to poor outcomes, including delayed presentation and nutritional challenges.
Main Results:
- High rates of SSIs (over 20%) and typhoid intestinal perforation (around 10%) are reported.
- Delayed presentation leads to high complication rates, with mortality approaching 41% for typhoid perforation in some areas.
- Acute appendicitis and soft-tissue infections like pyomyositis also present significant challenges.
Conclusions:
- Surgical infections pose a substantial threat to African children, characterized by high complication and mortality rates.
- Improved infection control, timely diagnosis, and effective surgical management are critical.
- Further research is needed to clarify the impact of HIV on surgical infections and to estimate economic consequences.
Abstract:
Infections and their complications requiring surgical intervention are a frequent presentation in African children. Surgical site infection (SSI) is common with rates over 20%, even after clean procedures. The high rates of SSI are due in part to lack of infection control and surveillance policies in most hospitals in Africa. SSI is attended by complications, long hospital stay, and some mortality, but the economic consequences are unestimated. Typhoid fever and typhoid intestinal perforation are major problems with perforation rates of approximately 10%, which is higher in older children. The ideal surgical treatment is arguable, but simple closure and segmental resection are the present effective surgical options. Because of delayed presentation, complications after surgical treatment are high with a mortality approaching 41% in some parts of Africa. Nutrition for these patients remains a challenge. Acute appendicitis, although not as common in African children, often presents rather late with up to 50% of children presenting with perforation and other complications, and mortality is approximately 4% is some settings. Pyomyositis and necrotizing fasciitis are the more common serious soft-tissue infections, but early recognition and prompt treatment should minimize the occasional mortality. Though common in Africa, the exact impact of human immunodeficiency virus infection on the spectrum and severity of surgical infection in African children is not clear, but it may well worsen the course of infection in these patients.
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