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Evaluation of an evidence-based practice implementation: prophylactic amiodarone following coronary artery

Mary C Hoffmann1

  • 1Christ Hospital, Cincinnati, Ohio, USA. mhoffmann@fuse.net

Dimensions of Critical Care Nursing : DCCN
|April 6, 2012
PubMed

Insights

Postoperative atrial fibrillation (POAF) after coronary artery bypass grafting is common. This study assessed a prophylactic amiodarone protocol

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Pharmacology

Background:

  • Postoperative atrial fibrillation (POAF) is the most common arrhythmia after coronary artery bypass grafting (CABG).
  • POAF leads to increased complications, prolonged hospitalization, and additional medical costs.
  • Prophylactic amiodarone is a known strategy for preventing POAF post-cardiac surgery.

Purpose of the Study:

  • To evaluate the feasibility and effectiveness of a current prophylactic amiodarone protocol in reducing POAF after CABG.
  • To identify perioperative risk factors associated with the development of POAF in patients undergoing CABG.

Main Methods:

  • Prospective evaluation of a prophylactic amiodarone treatment protocol.
  • Assessment of POAF incidence and related perioperative factors.
  • Comparison of outcomes with established benchmarks for POAF prevention.

Main Results:

  • The prophylactic amiodarone protocol demonstrated feasibility and effectiveness in reducing POAF incidence.
  • Analysis identified specific perioperative risk factors contributing to POAF development.
  • Outcomes were comparable to previously validated amiodarone protocols.

Conclusions:

  • The current prophylactic amiodarone protocol is a safe and effective strategy for POAF prevention following CABG.
  • Understanding perioperative risk factors can aid in targeted prevention strategies.
  • Implementation of this protocol may improve patient outcomes and reduce healthcare costs.

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