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Updated: May 23, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Diabetes and cancer (1): evaluating the temporal relationship between type 2 diabetes and cancer incidence
J A Johnson1, B Carstensen, D Witte
1School of Public Health, University of Alberta, 2040 Li Ka Shing Center, Edmonton, AB, Canada T6G 2E1. jeff.johnson@ualberta.ca
Abstract:
Substantial evidence suggests that people with type 2 diabetes have an increased risk of developing several types of cancers. These associations may be due to a number of direct and indirect mechanisms. Observational studies of these associations, including the potential role for glucose-lowering therapy, are being increasingly reported, but face a number of methodological challenges. This paper is the first of two review papers addressing methodological aspects underpinning the interpretations of links between diabetes and cancer, and suggests potential approaches to study designs to be considered in observational studies. This paper reviews factors related to cancer incidence in the diabetic population; the second paper relates to studies of cancer mortality.
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