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Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
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NALCN: a regulator of pacemaker activity.

Tom Z Lu1, Zhong-Ping Feng

  • 1Department of Physiology, Faculty of Medicine, University of Toronto, 3306 Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.

Molecular Neurobiology
|April 6, 2012
PubMed
Summary

The NALCN channel, crucial for pacemaker cell function, conducts a background sodium current that influences cell excitability and biological rhythms. This review details its physiology and role in pacemaker activity.

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