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Long-term outcome of infrapopliteal catheter-based intervention for critical limb ischemia

Nick N Abedi1, Daniel L Davenport, Nikolaos Karagiorgos

  • 1University of Kentucky Medical Center, Division of Vascular Surgery; Veterans Affairs Medical Center, Lexington, Kentucky, USA.

The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
|April 6, 2012
PubMed

Insights

Endoluminal interventions for tibioperoneal occlusive disease show a 63% limb salvage rate. This percutaneous approach may be the preferred initial treatment for critical limb ischemia.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Endovascular Therapy

Background:

  • Percutaneous treatment of tibioperoneal occlusive disease offers lower morbidity than bypass surgery.
  • Long-term patency and limb salvage rates for endovascular interventions require further documentation.

Purpose of the Study:

  • To assess the long-term outcomes of endoluminal interventions for tibioperoneal lesions.
  • Evaluate limb salvage and amputation-free survival after infrapopliteal interventions.

Main Methods:

  • Retrospective analysis of patients undergoing infrapopliteal catheter-based intervention for critical limb ischemia.
  • Inclusion of demographics, comorbidities, vascular measurements (ABI), intervention type, and follow-up data.
  • Statistical analysis using t-tests, Cox regression, and Kaplan-Meier survival analysis.

Main Results:

  • Technical success achieved in 75% of 35 patients.
  • Significant increase in Ankle-Brachial Index (ABI) post-intervention (0.62 to 0.81, P=0.02).
  • Overall limb salvage rate of 63%; better outcomes with isolated infrapopliteal interventions.

Conclusions:

  • Endoluminal interventions provide an acceptable limb salvage rate for tibioperoneal occlusive disease.
  • Percutaneous treatment may be the preferred initial therapy for critical limb ischemia.
  • Further studies on long-term patency are warranted.
Abstract

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