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Updated: May 23, 2026
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Retinal optical coherence tomography manifestations of intraocular lymphoma
Tin Yan Alvin Liu1, Mohamed Ibrahim, Millena Bittencourt
1Retinal Imaging Research and Reading Center, Wilmer Eye Institute, Johns Hopkins University, 600 North Wolfe Street, Maumenee 745, Baltimore, MD, 21287, USA.
Purpose:
Primary central nervous system lymphoma (PCNSL) is a rare disease. The index report describes a patient with intraocular lymphoma secondary to recurrent PCNSL and corresponding retinal findings on spectral domain optical coherence tomography (SD-OCT).
Methods:
Case report.
Results:
OCT changes were documented and correlated with the clinical course of intraocular lymphoma progression in the index patient. The OCT changes, manifested as hyperreflective material accumulation in the intraretinal and subretinal pigment epithelial spaces, were caused by lymphomatous infiltration.
Conclusion:
SD-OCT can be useful in diagnosing and monitoring the progression or regression of intraocular lymphoma with retinal involvement.
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