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Published on: October 31, 2012
Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax
Viola K T Leung1, Stephen S H Suen, Y H Ting
1Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. kittongl@cuhk.edu.hk
Abstract:
Chylothorax is a rare congenital condition associated with significant perinatal mortality and morbidity. Previous treatments with repeated thoracocentesis or thoracoamniotic shunting were technically demanding, and associated with significant procedure-related complications and neonatal complications. Here we report the first successful case in Hong Kong treated by a simple and effective intervention, namely pleurodesis with OK-432, in a fetus presenting at 20 weeks of gestation with bilateral pleural effusion.
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