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Updated: May 23, 2026
05:17
Intravenous Injections in Neonatal Mice
Published on: November 11, 2014
Opioid infusions in the neonatal intensive care unit
Amanda Suarez1, David C Knoppert, David S C Lee
1London Health Sciences Centre.
Summary
Opioid infusion dosing in neonates generally followed guidelines, but supplemental opioid use was common, especially for procedures. Pain assessment documentation was notably poor in the NICU.
Area of Science:
- Neonatal intensive care
- Pharmacology
- Pain management
Background:
- Opioid infusions are used for neonatal pain and sedation.
- Adherence to in-house guidelines and pain assessment practices are crucial for safe and effective neonatal care.
Purpose of the Study:
- To compare neonatal opioid infusion use against in-house guidelines.
- To evaluate the use of pain assessment tools and supplemental opioid administration.
Main Methods:
- Retrospective chart review of neonates receiving opioid infusions (Nov 2005-Nov 2006).
- Data included patient details, opioid dosing, duration, supplemental use, and pain assessment documentation.
Main Results:
- 65 neonates received opioid infusions; reasons for use varied, with 31% lacking documented indication.
- 46% received supplemental opioids, primarily for procedures.
- Neonatal Pain, Agitation and Sedation Scale scores were documented in only 9% of daily assessments.
Conclusions:
- Neonatal opioid infusion dosing aligned with handbook recommendations.
- Significant supplemental opioid use occurred, mainly for procedural pain.
- Poor documentation of opioid use indications and pain assessments was identified.
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