Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Dosage Regimen: Multiple Oral Dosage01:25

Dosage Regimen: Multiple Oral Dosage

Understanding how a drug's concentration fluctuates within the body over time is crucial in pharmacokinetics, particularly with multiple oral doses. A graphical representation of multiple oral dosages provides insight into these dynamics. Typical accumulation curves of a drug's concentration in the body reveal a sawtooth pattern, indicating periodic peaks and troughs correlating with each dose administration and the drug's subsequent elimination.The plasma concentration at any time during an...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of US Pediatric Pharmacists Incomes: A Gender Comparison Survey Study by the Pediatric Pharmacy Association, Practice-Based Research Network.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same author

Improving Pancreatic Function With Elexacaftor/Tezacaftor/Ivacaftor.

Pediatric pulmonology·2026
Same author

One Size May Not Fit All: A Case Series.

Pediatric pulmonology·2026
Same author

Inclusion matters: Describing CF health inequities in American Indian/Alaska Native individuals in Oklahoma.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society·2026
Same author

Shifting perspectives: diphenhydramine usage in anaphylaxis and urticaria across US emergency departments.

The American journal of emergency medicine·2025
Same author

Survey of Diabetes Technology in the Pediatric Inpatient Setting.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2025
Same journal

Ganciclovir Therapeutic Drug Monitoring in Critically Ill Pediatric Patients Receiving Continuous Renal Replacement Therapy.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same journal

Commentary on "Examining the Evidence Around Acetaminophen and Autism Risk".

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same journal

Sweet or Salty: Comparing Dextrose and Sodium Acetate Umbilical Arterial Catheter Fluids.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same journal

A Case of Prolonged Serotonin Toxicity After Fluoxetine Ingestion in an Adolescent Patient.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same journal

Efficacy and Safety of Tranexamic Acid in Pediatric Trauma: A Systematic Review and Meta-Analysis.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
Same journal

Heparin Resistance - A Reality or Fallacy.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG·2026
See all related articles

Related Experiment Video

Updated: May 23, 2026

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
09:17

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Published on: January 2, 2017

Once-daily amoxicillin for pharyngitis.

Megan Andrews1, Michelle Condren

  • 1University of Oklahoma College of Pharmacy.

The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG
|April 6, 2012
PubMed
Summary
This summary is machine-generated.

A once-daily antibiotic regimen for group A β-hemolytic streptococcal pharyngitis (GABHS) improves patient compliance and prevents rheumatic fever. Amoxicillin offers an effective and cost-efficient once-daily treatment option.

Related Experiment Videos

Last Updated: May 23, 2026

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
09:17

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Published on: January 2, 2017

Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Pediatrics

Background:

  • Group A β-hemolytic streptococcal pharyngitis (GABHS) can lead to rheumatic fever, a serious complication.
  • Current treatment guidelines often involve multiple daily antibiotic doses, potentially impacting patient adherence.
  • Improving compliance is crucial for effective GABHS treatment and secondary prevention of rheumatic fever.

Purpose of the Study:

  • To evaluate the efficacy and compliance of a once-daily antibiotic regimen for GABHS.
  • To assess the cost-effectiveness of once-daily amoxicillin compared to other GABHS treatments.
  • To support the American Heart Association's recommendation for once-daily amoxicillin.

Main Methods:

  • Review of existing literature and FDA-approved once-daily GABHS treatments.
  • Comparative analysis of antibiotic costs and dosing frequencies.
  • Assessment of amoxicillin's efficacy in once-daily regimens versus conventional dosing.

Main Results:

  • Once-daily amoxicillin is a cost-effective option for GABHS treatment.
  • Alternative once-daily antibiotics (azithromycin, cefadroxil, etc.) are available but more expensive.
  • Once-daily amoxicillin demonstrates comparable efficacy to multiple daily dosing regimens.

Conclusions:

  • Once-daily amoxicillin is an effective and affordable strategy for treating GABHS.
  • This regimen enhances patient compliance and aids in rheumatic fever prevention.
  • Amoxicillin's once-daily dosing presents a viable alternative to conventional penicillin treatments.