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Related Concept Videos

Transmission Shafts: Problem Solving01:09

Transmission Shafts: Problem Solving

Designing a solid shaft that transmits power from a motor to a machine tool involves a series of calculations to ensure the shaft can withstand the stresses applied by bending moments and torques. First, calculate the torque exerted on the gear, considering the power transmitted by the shaft and its rotational speed. Following this, compute the tangential forces acting on the gears, which directly relate to the torque and the gear radius.
Next, use bending moment diagrams for the shaft to...
Design of Transmission Shafts01:16

Design of Transmission Shafts

The design of a transmission shaft is governed by two primary specifications: the power it transmits and its rotational speed. These parameters guide the selection of the shaft's material and cross-sectional dimensions, ensuring that the material's maximum shearing stress remains within the elastic limit while transmitting the desired power at the given speed. The system's power is intrinsically linked to the applied torque. The torque applied to the shaft can be calculated by reconfiguring the...
Rolling Resistance: Problem Solving01:17

Rolling Resistance: Problem Solving

Rolling resistance, also known as rolling friction, is the force that resists the motion of a rolling object, such as a wheel, tire, or ball, when it moves over a surface. It is caused by the deformation of the object and the surface in contact with each other, as well as other factors like internal friction, hysteresis, and energy losses within the materials. Rolling resistance opposes the object's motion, requiring additional energy to overcome it and maintain movement. In practical...
Rolling Resistance01:21

Rolling Resistance

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Internal Combustion Engine01:20

Internal Combustion Engine

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Updated: May 23, 2026

New Variations for Strategy Set-shifting in the Rat
09:45

New Variations for Strategy Set-shifting in the Rat

Published on: January 23, 2017

10 years, still shifting gears.

Katherine T Adams

    Biotechnology Healthcare
    |April 6, 2012
    PubMed
    Summary

    Managing biologic drugs remains challenging due to complex access and cost issues. Future strategies are needed to refine these management techniques for payers and ensure patient access to innovative therapies.

    Area of Science:

    • Health Economics
    • Pharmaceutical Management
    • Biotechnology

    Background:

    • The modern biologics era, spanning a decade, highlights persistent challenges in managing access and costs.
    • Biologics present unique complexities compared to traditional pharmaceuticals, necessitating specialized management approaches.
    • Current cost- and access-management techniques for biologics are not yet fully optimized.

    Purpose of the Study:

    • To investigate the reasons behind the difficulties in managing biologic drugs compared to other pharmaceuticals.
    • To explore and propose effective strategies for payers to address future challenges in biologic drug management.
    • To enhance understanding of the evolving landscape of biologic therapeutics and their economic impact.

    Main Methods:

    • Literature review of existing biologics management strategies.

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    Published on: September 18, 2012

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    Last Updated: May 23, 2026

    New Variations for Strategy Set-shifting in the Rat
    09:45

    New Variations for Strategy Set-shifting in the Rat

    Published on: January 23, 2017

    Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
    11:12

    Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

    Published on: September 18, 2012

  • Comparative analysis of biologics versus traditional small-molecule drug management.
  • Payer-focused qualitative research on current and future challenges.

    • Main Results:

    • Biologics' complexity (e.g., manufacturing, administration, cold chain) significantly complicates management.
    • Lack of standardized pathways and high unit costs contribute to access barriers.
    • Existing payer models often struggle to adapt to the rapid innovation and pricing of biologics.

    Conclusions:

    • Refined, adaptive strategies are crucial for effective biologic drug management.
    • Payers require innovative approaches to balance cost containment with patient access to novel biologics.
    • Addressing the unique characteristics of biologics is essential for sustainable healthcare systems.