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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

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[Not Available].

Jean-François Bussières¹, Andrei Chiveri, Denis Lebel

¹, B. Pharm., M.Sc., est chef du Département de pharmacie et de l'Unité de recherche en pratique pharmaceutique au CHU Sainte-Justine et professeur titulaire de clinique à la Faculté de pharmacie de l'Université de Montréal, Montréal, Québec.

The Canadian Journal of Hospital Pharmacy

|April 6, 2012

Summary

This summary is machine-generated.

Drug shortages significantly impact hospital pharmacies, with 2400 shortages and over 258,000 out-of-stock days recorded between 2006-2010. A few manufacturers and specific drug classes, like central nervous system and anti-infective agents, were disproportionately affected.

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Area of Science:

Pharmacy Practice
Health Services Research
Pharmacoeconomics

Context:

Drug shortages represent a persistent challenge in contemporary pharmacy practice.
The increasing frequency and duration of shortages necessitate comprehensive data analysis.

Purpose:

To quantify the annual incidence and duration of drug shortages in Canadian hospitals.
To identify manufacturers and therapeutic classes most affected by drug supply disruptions.

Summary:

A retrospective analysis of hospital medication supply contracts in Quebec (2006-2010) identified 2400 shortages totaling 258,105 out-of-stock days.
Four manufacturers accounted for 50% of shortages, while central nervous system, anti-infective, and cardiovascular drugs represented 50% of affected therapeutic classes.
The study highlights the widespread impact of drug shortages across numerous manufacturers and drug categories.

Impact:

Provides the first Canadian data on the scope of drug shortages within the hospital sector.
Informs strategies for mitigating the impact of drug shortages on patient care and healthcare systems.
Underscores the need for further research into the root causes and consequences of drug supply chain vulnerabilities.