Related Experiment Video

Updated: Aug 3, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

Indications for use of ketoconazole in management of metastatic prostate cancer

F C Lowe1, M H Bamberger

  • 1Department of Urology, St. Luke's/Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York.

Urology
|December 1, 1990
PubMed

Insights

Ketoconazole offers a valuable short-term androgen ablation option for metastatic prostate cancer, particularly when other treatments are contraindicated or immediate response is needed. It is not ideal for long-term hormonal therapy.

Area of Science:

  • Oncology
  • Urology
  • Pharmacology

Background:

  • Metastatic prostate carcinoma requires androgen ablation therapy.
  • Standard treatments include oral estrogens and surgical castration.
  • Newer androgen ablation methods are being explored.

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