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Related Experiment Video

Updated: May 23, 2026

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
07:30

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

Published on: March 7, 2018

A solution-based nano-plasmonic sensing technique by using gold nanorods.

Fu Han Ho1, Yung-Han Wu, Masaki Ujihara

  • 1Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan, ROC. fuhanho@mail.ntust.edu.tw

The Analyst
|April 6, 2012
PubMed
Summary

We developed a new label-free nanosensor using gold nanorods to monitor solution concentrations and dielectric constants. This localized surface plasmon resonance (LSPR) technique offers precise, real-time analysis for microfluidic and cellular studies.

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Area of Science:

  • Nanotechnology
  • Plasmonics
  • Analytical Chemistry

Background:

  • Monitoring solution concentration and dielectric properties is crucial for various scientific disciplines.
  • Existing methods may lack sensitivity, real-time capabilities, or require labels.

Purpose of the Study:

  • To demonstrate a novel, label-free nanosensing technique for monitoring solution concentration and dielectric constant variations.
  • To utilize the localized surface plasmon resonance (LSPR) of gold nanorods for sensing applications.

Main Methods:

  • Fabrication of gold nanorods with narrow size distribution.
  • Characterization using transmission electron microscopy and optical absorption spectroscopy.
  • Analytical calculation to correlate LSPR band with nanorod aspect ratio.

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Last Updated: May 23, 2026

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
07:30

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

Published on: March 7, 2018

Fabrication of Periodic Gold Nanocup Arrays Using Colloidal Lithography
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Main Results:

  • Successful demonstration of a nanosensor based on gold nanorod LSPR.
  • Accurate detection of diffusion processes and saturation concentration of hexadecyltrimethylammonium bromide.
  • Simultaneous measurement of effective dielectric constants of the medium.

Conclusions:

  • The developed LSPR nanosensor is a sensitive and label-free tool for analyzing nano-scale variations.
  • This technique can be applied to study mixing or reaction processes in micro/nanofluidic channels.
  • It holds potential for investigating biological interactions within cellular environments.