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Published on: February 9, 2021
Pre-terminal renal insufficiency in a patient with enteric hyperoxaluria: effect of medical management on renal
L Pipeleers1, K M Wissing, Y Pirson
1Dept. of Nephrology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Belgium. lissa.pipeleers@uzbrussel.be
Abstract:
Enteric hyperoxaluria causes tubular deposition calcium oxalate crystals and severe chronic interstitial nephritis. We describe a patient with pre-terminal renal failure due to oxalate nephropathy after ileal resection. Increased oral hydration, low oxalate diet, and oral calcium carbonate and potassium citrate supplements resulted in a significant improvement of renal function. During the three-year follow-up, urinary oxalate concentration was repeatedly reduced below the crystallization threshold and serum creatinine decreased from 4.5 to 1.7 mg/dL. This case illustrates the benefit of combining and optimizing dietary and medical management in enteric hyperoxaluria, even in patients with advanced chronic kidney disease.
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