[Pharmacological and clinical profile of tiaprofenic acid]

Tiaprofenic acid is a new generation anti-inflammatory drug synthesized to be a valid alternative to both cortisone preparations and other NSADs since it is less toxic yet equally effective. Its anti-inflammatory, analgesic, antipyretic activity is due to a particular interference mechanism active in the early phases of the inflammatory process (PG synthesis inhibition, stabilization of lysosomal membranes). Thanks to its good trophism toward tissues in the otolaryngological area and its tolerability this drug would appear particularly suited for the treatment of inflammatory E.N.T. pathologies.