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[Tiaprofenic acid: a clinical study of 1186 patients with inflammatory ORL diseases]
1Divisione ORL, Ospedale Grande degli Infermi di Viterbo.
Abstract:
A multicenter trial is presented involving 39 Italian university and hospital centers and 1186 patients (mean age 37.6 +/- 0.46 years) suffering from phlogistic aural (33.7%), rhino-sinusal (22.5%) or pharyngolaryngeal (43.8%) pathology. These patients were treated with 600 mg of tiaprofenic acid daily for a period of 7 days. The drug was administered either as monotherapy (53.2% of the cases) or in association with antibiotics (46.8%). Tiaprofenic acid showed similar therapeutic efficacy under both conditions, carrying out a clear antipyretic, anti-inflammatory, mainly analgesic action in the pathologies of all three otolaryngological areas. Treatment tolerance and compliance proved quite good. Only 20% of the patients claimed light side effects. The treatment was interrupted only in 18 (1.5%) of the 1186 patients studied.
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