Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

Cerebral Hemispheres

Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...

Cerebrum: Anatomical Overview I

Cerebrum: Anatomical Overview I

The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The role of persistent inflammation in failed recovery after perinatal brain injury: is resolution the cure?

Journal of neuroinflammation·2026

Same author

Advocacy efforts by the American Society of Pediatric Neurosurgeons: evolving priorities, ongoing initiatives, and future directions.

Journal of neurosurgery. Pediatrics·2026

Same author

Variable Treatment Effects of Cranial Surgery in Pediatric Severe Traumatic Brain Injury.

Neurosurgery·2026

Same author

Engineered neuroglial organoids as living neural interfaces for restorative neurosurgery.

Neurosurgical focus·2026

Same author

Emergency Medical Services Time on Scene Associated with Reduced Dead-on-Arrival Status Among Pediatric Patients with Severe Traumatic Brain Injury.

Prehospital emergency care·2025

Same author

Pott's puffy tumor in the post-COVID era.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2025

Search research articles

Related Experiment Video

Updated: May 23, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

Anatomic hemispherectomy: historical perspective.

Biji Bahuleyan¹, Shenandoah Robinson, Ajith Rajappan Nair

¹Division of Pediatric Neurosurgery, Rainbow Babies and Children's Hospital, The Neurological Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

World Neurosurgery

|April 7, 2012

Summary

This summary is machine-generated.

Surgical treatments for hemispheric epilepsy evolved from radical resections to less invasive disconnection procedures. Newer techniques offer comparable seizure control with reduced complications.

Keywords:

AH Anatomic hemispherectomy Epilepsy Hemispherectomy Hemispherotomy History SH Subtotal hemispherectomy

More Related Videos

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Related Experiment Videos

Last Updated: May 23, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

Area of Science:

Neurosurgery
Epileptology

Background:

Hemispheric epilepsy presents complex treatment challenges.
Surgical interventions have evolved significantly over time.

Observation:

Anatomic hemispherectomy (AH) was initially popular but associated with risks.
Functional hemispherectomy and hemispherotomy were developed to mitigate AH's morbidity.
Superficial cerebral hemosiderosis impacted AH's favorability.

Findings:

Surgery for hemispheric epilepsy has transformed from radical resections to less invasive disconnection procedures.
Less invasive techniques aim to minimize brain removal while maximizing white matter disconnections.
Newer disconnection techniques achieve near-comparable seizure control to radical AH with lower complication rates.

Implications:

Surgical strategies for hemispheric epilepsy continue to advance.
Minimally invasive approaches offer improved safety profiles for patients.
Further research into optimizing disconnection techniques is warranted for enhanced patient outcomes.