Related Experiment Video
Updated: May 23, 2026

09:37
Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Dermoscopic criteria and basal cell carcinoma
1Melanoma Unit, Dermatology Department, Barcelona Clinical Hospital, IDIBAPS, Barcelona, Spain. susipuig@gmail.com
Summary
Dermoscopy significantly aids in diagnosing basal cell carcinoma (BCC), the most common skin cancer. Recognizing classical and non-classical dermoscopic features improves early detection and avoids misdiagnosis.
Area of Science:
- Dermatology
- Oncology
- Medical Imaging
Background:
- Basal cell carcinoma (BCC) is the most prevalent skin cancer in fair-skinned individuals.
- Dermoscopy enhances the diagnostic accuracy of skin lesions, including early and subtle BCC.
- Accurate diagnosis is crucial for timely and effective treatment of BCC.
Purpose of the Study:
- To review and consolidate the dermoscopic criteria for diagnosing basal cell carcinoma (BCC).
- To highlight both classical and non-classical dermoscopic features of BCC.
- To emphasize the importance of recognizing diverse dermoscopic patterns for improved early diagnosis.
Main Methods:
- Review of established dermoscopic algorithms for BCC diagnosis.
- Compilation of classical dermoscopic features (e.g., lack of pigment network, ulceration, specific structures).
- Inclusion of non-classical and recently described features (e.g., pink-white areas, Chrysalides, Rosetas) and polarized dermoscopy findings.
Main Results:
- Classical BCC dermoscopy includes lack of pigment network plus specific structures like ulceration, maple-leaf like structures, blue-gray globules, blue-ovoid nests, arborizing vessels, and spoke-wheel structures.
- Non-classical features, often seen in superficial BCC, encompass pink-white areas, concentric structures, multiple erosions, blue-gray dots, and fine vessels.
- Specific dermoscopic findings for Fibroepithelioma of Pinkus and structures visible with polarized dermoscopy (white shiny streaks) are also noted.
Conclusions:
- Comprehensive knowledge of classical, non-classical, and specialized dermoscopic criteria is essential for accurate BCC diagnosis.
- Improved understanding of these dermoscopic features can prevent diagnostic errors.
- Enhanced dermoscopic expertise facilitates the early recognition of basal cell carcinoma, leading to better patient outcomes.
Related Concept Videos
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cellular Adaptation IV: Dysplasia and Metaplasia
DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...

