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Buschke -Loewenstein tumor: identification of HPV type 6 and 11
Juliana Casagrande Tavoloni Braga1, Sidney Roberto Nadal, Monica Stiepcich
1Dermatology and Skin Cancer Center, AC Camargo Hospital, São Paulo, SP, Brazil. jcasagrande.dermato@gmail.com
Anais Brasileiros De Dermatologia
|April 7, 2012
Summary
Giant condyloma acuminatum, a rare HPV-related condition, was successfully treated surgically in a male patient. The tumor showed no recurrence after 20 months, indicating effective management of this locally destructive lesion.
Area of Science:
- Dermatology
- Oncology
- Virology
Background:
- Giant condyloma acuminatum (Buschke-Loewenstein tumor) is a rare manifestation of human papillomavirus (HPV) infection.
- It is characterized by slow growth and locally destructive behavior, often mimicking squamous cell carcinoma.
Observation:
- A male patient presented with an extensive, slow-growing giant condyloma acuminatum.
- The lesion involved the inguinal, penile, scrotal, perineal, and perianal regions, exhibiting significant local destruction.
Findings:
- Surgical excision was performed as the primary treatment modality.
- In situ hybridization confirmed the presence of HPV types 6 and 11 within the tumor.
- Post-operative follow-up for 20 months revealed no signs of recurrence.
Implications:
- This case highlights the importance of surgical management for large and destructive Buschke-Loewenstein tumors.
- Complete surgical resection can lead to favorable long-term outcomes with no recurrence.
- Understanding the HPV etiology is crucial for managing these lesions.
