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Visualization and Quantification of High-Dimensional Cytometry Data using Cytofast and the Upstream Clustering Methods FlowSOM and Cytosplore
Published on: December 12, 2019
The new and computationally efficient MIL-SOM algorithm: potential benefits for visualization and analysis of a
Tonny J Oyana1, Luke E K Achenie, Joon Heo
1GIS Research Laboratory for Geographic Medicine, Department of Geography and Environmental Resources, Southern Illinois University, 1000 Faner Drive, MC 4514, Carbondale, IL 62901, USA. tjoyana@siu.edu
Abstract:
The objective of this paper is to introduce an efficient algorithm, namely, the mathematically improved learning-self organizing map (MIL-SOM) algorithm, which speeds up the self-organizing map (SOM) training process. In the proposed MIL-SOM algorithm, the weights of Kohonen's SOM are based on the proportional-integral-derivative (PID) controller. Thus, in a typical SOM learning setting, this improvement translates to faster convergence. The basic idea is primarily motivated by the urgent need to develop algorithms with the competence to converge faster and more efficiently than conventional techniques. The MIL-SOM algorithm is tested on four training geographic datasets representing biomedical and disease informatics application domains. Experimental results show that the MIL-SOM algorithm provides a competitive, better updating procedure and performance, good robustness, and it runs faster than Kohonen's SOM.

