Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Added diagnostic value and impact on antimicrobial therapy of 16S rRNA PCR and amplicon sequencing on resected heart valves in infective endocarditis: a prospective cohort study.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseasesยท2017
Same author

Post-operative echocardiographic evaluation of bioprosthetic mitral valve implantation in sheep.

Laboratory animalsยท2014
Same author

Nosocomial infective endocarditis: should the definition be extended to 6 months after discharge.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseasesยท2008
Same author

Methicillin-resistant versus methicillin-sensitive Staphylococcus aureus infective endocarditis.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiologyยท2008
Same author

Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice.

British journal of pharmacologyยท2007
Same author

Infective endocarditis treated with linezolid: case report and literature review.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiologyยท2006
Same journal

Air pollution in Belgium: will we be able to comply with the European standards?

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgieยท2012
Same journal

The influence of air pollution on health: mechanistic implications.

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgieยท2012
Same journal

Air pollution and health--air quality standards.

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgieยท2012
Same journal

[Worry about talent in first line health care].

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgieยท2012
Same journal

[Piet de Somer, the University of Leuven and the Belgium poliovaccine in 1956-57].

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgieยท2012
Same journal

[Emergency guidelines for cosmetic procedures and esthetic skin treatment: recommendations of the medical establishment].

Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgieยท2012
See all related articles

Related Experiment Video

Updated: May 23, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

Infective endocarditis.

M-C Herregods1

  • 1Division of Cardiology, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, O&N I Herestraat 49--B 3000 Leuven.

Verhandelingen - Koninklijke Academie Voor Geneeskunde Van Belgie
|April 10, 2012
PubMed
Summary
This summary is machine-generated.

Infectious endocarditis diagnosis is challenging due to varied symptoms. Early diagnosis and prompt treatment, including antibiotics and surgery, are crucial for better outcomes in this complex heart valve infection.

More Related Videos

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Related Experiment Videos

Last Updated: May 23, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

Published on: June 4, 2012

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Infectious endocarditis (IE) diagnosis is often delayed due to nonspecific and variable clinical presentations.
  • While the Duke criteria have improved diagnosis, IE remains a significant challenge with stable incidence.
  • Predisposing factors are shifting towards degenerative valvular disease and intravascular foreign material.

Purpose of the Study:

  • To highlight the diagnostic challenges and evolving epidemiology of infectious endocarditis.
  • To emphasize the importance of early diagnosis and prompt, multidisciplinary management.
  • To discuss the complications, treatment strategies, and factors influencing mortality in IE.

Main Methods:

  • Review of clinical, bacteriological, and echocardiographical findings integrated by Duke criteria.
  • Analysis of epidemiological trends, predisposing factors, and complications.
  • Evaluation of current treatment paradigms including antibiotic therapy and cardiac surgery indications.

Main Results:

  • IE frequently presents with atypical symptoms, complicating early diagnosis.
  • Complications include heart failure (approx. 50%) and embolic events (approx. 33%), often occurring early in treatment.
  • Staphylococcus aureus with artificial valves increases risk of perivalvular abscesses.

Conclusions:

  • Prompt initiation of high-dose, tailored antibiotic therapy (4-6 weeks) is essential.
  • Early cardiac surgery is often required ( >50% of patients) and associated with better outcomes.
  • Despite advances, mortality remains high due to aggressive pathogens and an aging, comorbid population.