Intra-operative floppy iris syndrome

Intra-operative floppy iris syndrome (IFIS) is a recently described phenomenon seen in patients undergoing cataract surgery who have taken tamsulosin, an alpha 1a-adrenergic antagonist used for benign prostatic enlargement. Incidence of even 90% has been reported in studies with majority of them being severe in nature. Prevention of intra-operative floppy iris syndrome by withdrawing tamsulosin pre-operatively has not shown consistent result. The risk of dangers of intra-operative floppy iris syndrome may be decreased by using preoperative atropine or by using visco-adaptive devices, intra-operatively.