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Cholecystitis

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...

Acute Pancreatitis I: Introduction

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Brain Abscess l: Introduction

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Acute Pancreatitis II: Clinical Manifestations and Management

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...

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Updated: May 23, 2026

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

Splenic abscess arising from acute cholecystitis.

Patrick Harnarayan¹, Vijay Naraynsingh, Seetharaman Hariharan

¹Department of Clinical Surgical Sciences, The University of the West Indies, St. Augustine, Trinidad, West Indies.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|April 10, 2012

Summary

A splenic abscess is a rare but dangerous condition. Early diagnosis is crucial, especially in patients with cholecystitis, to prevent life-threatening complications.

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Last Updated: May 23, 2026

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

Area of Science:

Surgical pathology
Abdominal imaging
Infectious disease

Background:

Splenic abscess is a rare and potentially fatal surgical emergency.
It is often associated with other intra-abdominal infections, such as hepatic abscess.
Prompt diagnosis and management are critical for patient survival.

Observation:

This case report details a splenic abscess occurring concurrently with cholecystitis.
Symptoms of splenic abscess are often nonspecific, complicating early identification.
A high index of suspicion is warranted in patients presenting with cholecystitis.

Findings:

The study highlights a rare association between splenic abscess and cholecystitis.
Non-specific symptoms necessitate a thorough diagnostic approach.
Fever and left upper quadrant pain in cholecystitis patients may indicate splenic abscess.

Implications:

Clinicians should consider splenic abscess in patients with cholecystitis, particularly those with fever and left upper quadrant pain.
Enhanced diagnostic vigilance can lead to earlier detection and improved outcomes.
Understanding these associations is key for effective management of complex abdominal infections.