Related Experiment Videos
[Expression and clinical significance of CD3, CD4 and COX-2 in non-small cell lung cancer]
Xiao Zhao1, Xiang Yan, Yan-Fang Ju
1Department of Medical Oncology, PLA General Hospital, Beijing 100853, China.
Aim:
To study expression and clinical significance of CD3, CD4 and COX-2 in non-small cell lung cancer (NSCLC).
Methods:
Expression of COX-2, CD3 and CD4 was detected by immunohistochemical staining in 37 cases of NSCLC. The correlation of CD3, CD4, COX-2 expressions and overall survival(OS) was evaluated with spearman rank correlation analysis.
Results:
The average surface density of CD3 and the average optical density of CD4 were significantly associated with OS of NSCLC patients after surgery (P<0.05). However, both two densities of COX-2 were correlated with survival time of patients (P>0.05).
Conclusion:
The expressions of CD3, CD4 were significantly associated with OS of NSCLC patients.