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Related Experiment Video

Updated: May 23, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
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Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

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A realistic deformable prostate phantom for multimodal imaging and needle-insertion procedures.

Nikolai Hungr1, Jean-Alexandre Long, Vincent Beix

  • 1UJF-Grenoble 1/CNRS/TIMC-IMAG UMR 5525, Grenoble, France. Nikolai.Hungr@imag.fr

Medical Physics
|April 10, 2012
PubMed
Summary

This study introduces a realistic deformable prostate phantom for multimodal imaging, crucial for validating new image-guided procedures. Its properties closely mimic human tissue, aiding research in prostate interventions.

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Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Prostate Cancer Research

Background:

  • Phantoms are essential for validating image-guided medical procedures.
  • Developing realistic phantoms improves the accuracy and safety of interventions.
  • Prostate interventions require phantoms that accurately simulate tissue properties and imaging characteristics.

Purpose of the Study:

  • To present a novel deformable prostate phantom for multimodal imaging (ultrasound, CT, MRI).
  • To enable realistic simulation of transperineal or transrectal needle-insertion procedures.
  • To provide a tool for preliminary validation of new prostate diagnostic and therapeutic techniques.

Main Methods:

  • Detailed manufacturing description of a polyvinyl chloride (PVC) prostate phantom.

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Last Updated: May 23, 2026

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  • Evaluation of material properties: speed of sound and stress-strain relationship.
  • Assessment of imaging characteristics, needle-insertion forces, and deformability.

    • Main Results:

    • The phantom's material exhibited viscoelastic properties similar to prostatic tissue (speed of sound: 1380 ± 20 m/s).
    • Stable mechanical and imaging characteristics were observed at cooler storage temperatures.
    • High-resolution imaging across modalities with accurate target segmentation (US-CT registration error: 0.66 mm) and realistic prostate mobility (2-4 mm displacement).

    Conclusions:

    • The developed prostate phantom demonstrates favorable characteristics compared to existing literature.
    • Its realistic deformability and multimodal imaging compatibility make it suitable for research.
    • This phantom can significantly advance the development of novel needle-based prostate diagnosis and therapy techniques.