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Updated: May 23, 2026

Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Monte Carlo simulation of breast imaging using synchrotron radiation
N T Fitousi1, H Delis, G Panayiotakis
1Department of Medical Physics, University of Patras, Patras, Greece.
Synchrotron radiation (SR) shows improved breast imaging performance compared to conventional mammography. A validated simulation model demonstrates SR
Area of Science:
- Medical Imaging
- Biophysics
- X-ray Physics
Background:
- Synchrotron radiation (SR) offers high-intensity X-rays, promising for advanced breast imaging.
- Evaluating SR breast imaging in situ is challenging due to limited facility access.
Purpose of the Study:
- Develop and validate a Monte Carlo simulation model for SR breast imaging.
- Assess the performance and contrast resolution of SR in breast imaging.
Main Methods:
- A simulation model replicating the SYRMEP beamline setup was created.
- Breast phantoms with varying compositions and air cavities were used for irradiation (16-28 keV).
- Model validation involved comparing simulated data with experimental results from a Gd(2)O(2)S detector.
Main Results:
- The simulation model demonstrated excellent agreement with experimental data (contrast correlation: 0.996).
- SR imaging exhibited superior image quality, including subject contrast and contrast-to-noise ratio.
- Optimal performance for contrast-to-noise ratio was observed within the 18-21 keV energy range.
Conclusions:
- SR technology demonstrates superior performance for breast imaging compared to conventional mammography.
- The validated simulation model facilitates comprehensive evaluation of SR for clinical breast imaging applications.
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