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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Practices and complications of vascular closure devices and manual compression in patients undergoing elective
Nathaniel R Smilowitz1, Ajay J Kirtane, Michael Guiry
1Center for Interventional Vascular Therapy, New York-Presbyterian Hospital, Columbia University Medical Center, New York, NY, USA.
Insights
Vascular closure devices (VCDs) show superior results compared to manual compression for hemostasis after coronary angiography and PCI. VCDs significantly reduce access complications, improving patient outcomes in these common cardiac procedures.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- Femoral arterial puncture is standard for coronary angiography and PCI.
- Access complications, though infrequent, increase morbidity and healthcare costs.
- Optimal hemostasis strategy remains debated, with no consensus on Vascular Closure Devices (VCDs) versus manual compression (MC).
Purpose of the Study:
- To compare the efficacy and safety of VCDs versus MC for hemostasis after elective transfemoral coronary procedures.
- To identify predictors of vascular access complications in patients undergoing coronary angiography and PCI.
Main Methods:
- Retrospective review and nested case-control study of 9,108 consecutive patients over 3 years.
- Analysis of vascular complications including bleeding, pseudoaneurysm, and infection.
- Comparison of outcomes between MC (28.3%) and VCD (71.7%) hemostasis strategies.
Main Results:
- Overall complication rate was low at 0.81%.
- VCD use was associated with significantly fewer complications (0.64%) compared to MC (1.24%, p=0.004).
- Older age and large femoral sheath use (7Fr-8Fr) were independent predictors of complications.
Conclusions:
- Vascular closure devices are associated with superior outcomes and fewer complications than manual compression for transfemoral coronary procedures.
- Careful selection of hemostasis strategy and closure device can further minimize complication rates.
- VCD use is a predictor of fewer vascular access complications.
Abstract:
Femoral arterial puncture is the most common access method for coronary angiography and percutaneous coronary interventions (PCIs). Access complications, although infrequent, affect morbidity, mortality, costs, and length of hospital stay. Vascular closure devices (VCDs) are used for rapid hemostasis and early ambulation, but there is no consensus on whether VCDs are superior to manual compression (MC). A retrospective review and nested case-control study of consecutive patients undergoing elective transfemoral coronary angiography and PCI over 3 years was performed. Hemostasis strategy was performed according to the operators' discretion. Vascular complications were defined as groin bleeding (hematoma, hemoglobin decrease ≥3 g/dl, transfusion, retroperitoneal bleeding, or arterial perforation), pseudoaneurysm, arteriovenous fistula formation, obstruction, or infection. Patients with postprocedure femoral vascular access complications were compared to randomly selected patients without complication. Data were available for 9,108 procedures, of which PCI was performed in 3,172 (34.8%). MC was performed in 2,581 (28.3%) and VCDs (4 different types) were deployed in 6,527 procedures (71.7%). Significant complications occurred in 74 procedures (0.81%), with 32 (1.24%) complications with MC and 42 (0.64%) with VCD (p = 0.004). VCD deployment failed in 80 procedures (1.23%), of which 8 (10%) had vascular complications. VCD use was a predictor of fewer complications (odds ratio 0.52, 95% confidence interval 0.33 to 0.83). In the case-control analysis, older age and use of large (7Fr to 8Fr) femoral sheaths were independent predictors of complications. In conclusion, the retrospective analysis of contemporary hemostasis strategies and outcomes in elective coronary procedures identified a low rate of complications (0.81%), with superior results after VCD deployment. Careful selection of hemostasis strategy and closure device may further decrease complication rates.
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