Related Experiment Video
Updated: May 23, 2026
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
[Immunohistochemical markers in the diagnosis of pigmented conjunctival lesions]
R M Bellido Muñoz1, I Domínguez Hidalgo, J L García Serrano
1Hospital Clínico San Cecilio, Granada, España. rbellido78@hotmail.com
Objective/Method:
The aim of this study was to assess the importance of immunohistochemical markers in the diagnosis of pigmented conjunctival lesions. Due to the difficulty of making an exact clinical diagnosis, the suspicion of malignancy requires the removal of the lesion and performing a histopathology study in which immunohistochemical markers may help to determine the nature of the lesion.
Cases Report/Discussion:
A case is presented of a 25 year-old woman with a pigmented lesion in the caruncle. It appeared recently and was growing fast with increasing pigmentation. Due to a suspicion of malignancy, the total lesion was removed. The microscopic study revealed cellular alterations which suggested malignancy. However, after carrying out immunohistochemical markers the diagnosis was conjunctival compound nevus.
