Related Experiment Videos
Epiretinal membrane contracture associated with macular prolapse
M A Zarbin1, R G Michels, W R Green
1Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.
Abstract:
We treated two patients with annular epiretinal membranes that produced unusual macular morphologic characteristics. Contracture of the membranes caused herniation of macular tissue through a hole in the center of the membrane. The membranes were removed surgically, and ultrastructural analysis disclosed cells with properties resembling myofibroblasts and apparent new vitreous collagen. Contracture of the cellular components probably produced tangential traction on the retina, which caused prolapse of the retinal tissue through a central defect in the membrane.
Insights
Annular epiretinal membranes can cause unusual macular changes. Surgical removal revealed myofibroblast-like cells and collagen, suggesting traction led to retinal tissue herniation.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Surgical Pathology
Background:
- Epiretinal membranes (ERMs) can affect retinal structure.
- Annular ERMs are less common and may present unique pathologies.
- Macular morphologic abnormalities require detailed investigation.