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Updated: May 23, 2026
04:36
Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
Published on: October 2, 2020
Hemoglobin variability does not predict mortality in peritoneal dialysis patients.
Ho-Ching Chen1, Kuan-Hsing Chen, Yu-Jr Lin
1Department of Nephrology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyun, Taiwan.
Chang Gung Medical Journal
|April 10, 2012
Summary
Hemoglobin variability in peritoneal dialysis patients does not predict mortality. While most patients had unstable or low hemoglobin, high amplitude fluctuations were linked to longer hospital stays, not death.
Area of Science:
- Nephrology
- Hematology
- Clinical Research
Background:
- Hemoglobin variability is studied in hemodialysis patients regarding mortality and comorbidity.
- Limited research exists on hemoglobin variability in peritoneal dialysis patients.
Purpose of the Study:
- To investigate hemoglobin variability in peritoneal dialysis patients.
- To evaluate its association with mortality, comorbidity, peritonitis, and hospitalization.
Main Methods:
- Monitored hemoglobin levels in 363 peritoneal dialysis patients over 2 years.
- Assessed variability against a target range (11-12.5 g/dL).
- Categorized patients into 6 groups based on hemoglobin patterns.
Main Results:
- Only 2% of patients maintained stable hemoglobin; 46.8% had consistently low levels.
- No significant differences in mortality, peritonitis, or hospitalization rates were found between groups.
- Patients with high amplitude hemoglobin fluctuations experienced longer hospital stays (p=0.008).
Conclusions:
- Hemoglobin variability does not appear to be a predictor of mortality in peritoneal dialysis patients.
- High amplitude fluctuations may correlate with increased healthcare utilization (hospital stay length).
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