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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Percentages of water, muscle, and bone decrease and lipid increases in early period after successful kidney
H Harada1, M Nakamura, K Hotta
1Department of Kidney Transplant Surgery and Urology, Sapporo City General Hospital, Sapporo, Japan. hiroshi.harada@doc.city.sapporo.jp
Transplantation Proceedings
|April 10, 2012
Summary
Successful kidney transplantation (KT) can alter body composition, leading to decreased muscle and bone mass, and increased fat. Post-transplant care should include strategies to manage these changes and prevent dyslipidemia.
Area of Science:
- Nephrology
- Transplantation Medicine
- Human Physiology
Background:
- Chronic kidney disease (CKD) significantly impacts body composition.
- Kidney transplantation (KT) is a potential treatment to restore body composition in CKD patients.
- Limited data exists on the practical changes in body composition following successful KT.
Purpose of the Study:
- To evaluate changes in body composition, including body mass index (BMI), water, fat, muscle, and bone mass.
- To assess alterations in lipid metabolism after kidney transplantation.
- To compare outcomes between different immunosuppressive protocols.
Main Methods:
- A cohort of 37 male and 18 female kidney recipients was studied.
- Body composition was analyzed using bioelectrical impedance before and 1 year after KT.
- BMI and serum lipid profiles were also measured and compared.
Main Results:
- No significant change in BMI was observed.
- A significant decrease in water and an increase in fat mass were noted post-KT.
- Muscle and bone mass significantly decreased, while lipid profiles (total cholesterol, LDL, triglycerides) worsened.
Conclusions:
- Successful KT can lead to unfavorable changes in body composition, including muscle atrophy and fat gain.
- Post-transplant dyslipidemia is a risk factor for cardiovascular disease and requires management.
- Dietary and exercise interventions are recommended to mitigate adverse body composition changes after KT.
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