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Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

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Low plasma adiponectin levels in panic disorder.

Cuneyt Unsal¹, Aytul Gursu Hariri, Omer Yanartas

¹Namık Kemal University, School of Medicine, Department of Psychiatry, Tekirdag, Turkey. drcunsal@gmail.com

Journal of Affective Disorders

|April 10, 2012

Summary

Patients with panic disorder (PD) have significantly lower plasma adiponectin levels. This finding suggests a potential link between PD and adiponectin, warranting further cardiac monitoring for these patients.

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Area of Science:

Endocrinology
Psychiatry
Cardiology

Background:

Panic disorder (PD) is a condition characterized by sudden episodes of intense fear.
Adiponectin is an adipokine with known roles in metabolic and cardiovascular health.

Purpose of the Study:

To investigate plasma adiponectin levels in patients diagnosed with panic disorder.
To explore potential correlations between panic disorder and adiponectin.

Main Methods:

A case-control study comparing 28 patients with PD and 23 healthy controls.
Measurement of plasma adiponectin, fasting glucose, lipids, and hemoglobin.
Statistical analysis including t-tests and ANCOVA, adjusting for BMI and gender.

Main Results:

No significant differences in glucose, cholesterol, triglycerides, LDL, HDL, or hemoglobin between groups.
Significantly lower mean adiponectin levels observed in the panic disorder group (26.96 ± 9.92 ng/ml) compared to controls (37.63 ± 23.17 ng/ml).
ANCOVA confirmed a significant effect of diagnosis on adiponectin levels after controlling for BMI and gender.

Conclusions:

Plasma adiponectin levels are significantly reduced in individuals with panic disorder.
Findings suggest a potential interaction between panic disorder and adiponectin.
Patients with panic disorder may require monitoring for cardiac issues due to altered adiponectin levels.