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Published on: March 25, 2019
Theranostic applications of nanoparticles in cancer
Naveed Ahmed1, Hatem Fessi, Abdelhamid Elaissari
1University of Lyon, F-69622, Lyon, France.
Abstract:
Nanoparticles are the moieties that have undergone the most investigation in recent years for biomedical applications. They are applied in the field of oncology in the same way as in other branches of biomedical nanotechnology. Regarding cancer, nanoparticles, and especially magnetic nanoparticles, are studied for diagnosis, drug delivery, gene delivery, bioseparation, hyperthermia, phototherapy, chemotherapy, imaging mechanisms, among other uses. Different techniques are used to prepare multifunctional nanoparticles and modify nanoparticle surfaces required for different applications. This review focuses on the basic theranostic approach, the different materials used in theranostics, theranostic applications and future directions based on recent developments in these areas.
Insights
Magnetic nanoparticles show promise for cancer diagnosis and treatment. This review explores their theranostic applications, materials, and future potential in oncology.
Area of Science:
- Biomedical Nanotechnology
- Oncology
- Nanomedicine
Background:
- Nanoparticles are extensively researched for biomedical uses, particularly in oncology.
- Magnetic nanoparticles offer diverse applications in cancer management, including diagnosis and therapy.
Purpose of the Study:
- To review the fundamental theranostic approach using nanoparticles in cancer.
- To discuss materials, applications, and future directions in nanoparticle-based cancer theranostics.
Main Methods:
- Review of recent developments in nanoparticle synthesis and surface modification for theranostics.
- Analysis of literature on the application of magnetic nanoparticles in oncology.
Main Results:
- Nanoparticles are versatile tools for cancer diagnosis, drug/gene delivery, and various therapeutic modalities like hyperthermia and phototherapy.
- Multifunctional nanoparticles are engineered using diverse preparation techniques and surface modifications.
Conclusions:
- Nanoparticle-based theranostics represent a significant advancement in personalized cancer care.
- Continued research into novel materials and applications will drive future progress in nanomedicine for oncology.
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