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Related Experiment Video

Updated: May 23, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid

Published on: June 17, 2025

Pemphigus foliaceus.

Ghalamkarpour Fariba¹, Azin Ayatollahi, Somayeh Hejazi

¹Shahid Beheshti University Shohada-e Tajrish Hospital, Tehran, Iran. fghalamkarpour@yahoo.com

Indian Pediatrics

|April 10, 2012

Summary

Pemphigus foliaceus is a rare autoimmune skin blistering disease. This report details an unusual case of erythrodermic pemphigus foliaceus in a pediatric patient.

Area of Science:

Dermatology
Autoimmunology
Pediatric Autoimmune Diseases

Background:

Pemphigus foliaceus is an autoimmune blistering condition primarily affecting the skin.
It has endemic and sporadic variants, with mucosal involvement being rare.
Erythrodermic presentation is uncommon, especially in children.

Observation:

A 12-year-old boy presented with a rare form of pemphigus foliaceus.
The patient exhibited an erythrodermic presentation of the disease.
This case highlights an unusual manifestation in a pediatric demographic.

Findings:

The case confirms the possibility of erythrodermic pemphigus foliaceus in children.
It underscores the variability in clinical presentation of this autoimmune disorder.

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Diagnostic and management considerations for pediatric erythrodermic pemphigus foliaceus are relevant.

Implications:

This case expands the understanding of pemphigus foliaceus clinical spectrum.
It emphasizes the need for considering rare dermatological conditions in pediatric erythroderma.
Further research into pediatric autoimmune blistering diseases is warranted.