Lane-Hamilton syndrome: association or coincidence
Sule Paksu1, Muhammet Sukru Paksu, Ayhan Gazi Kalayci
1Department of Pediatrics, Ondokuz Mayys University Faculty of Medicine, Samsun, Turkey. sukrupaksu@yahoo.com
Indian Pediatrics
|April 10, 2012
Summary
Idiopathic pulmonary hemosiderosis (IPH) and celiac disease (CD) rarely occur together. A gluten-free diet significantly improved both intestinal and pulmonary symptoms in a child with this rare combination.
Area of Science:
- Pediatric Pulmonology
- Gastroenterology
- Rare Diseases
Background:
- Idiopathic pulmonary hemosiderosis (IPH) is a rare lung disease.
- Celiac disease (CD) is an autoimmune disorder triggered by gluten.
- The co-occurrence of IPH and CD is exceptionally uncommon.
Observation:
- A 4.5-year-old girl presented with cough, dyspnea, pallor, and abdominal pain.
- She exhibited signs of respiratory distress, including tachycardia and low oxygen saturation.
- Initial symptoms suggested both gastrointestinal and pulmonary involvement.
Findings:
- The patient was diagnosed with both celiac disease and idiopathic pulmonary hemosiderosis.
- Treatment with a gluten-free diet and corticosteroids was initiated.
- Both the intestinal and pulmonary symptoms showed significant improvement.
Implications:
- This case highlights the importance of considering celiac disease in children with unexplained pulmonary hemorrhage.
- A gluten-free diet can be a crucial therapeutic intervention for the pulmonary manifestations of IPH when associated with CD.
- Early diagnosis and combined treatment can lead to favorable outcomes in this rare condition.
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