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Selective photoreceptor cell loss in hypoxic ischemia
R E Holman1, R L Peiffer, T W Bouldin
1Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill 27599-7040.
Annals of Ophthalmology
|September 1, 1990
Abstract:
We studied the histopathologic changes in the brain and eye of a 5 1/2-month-old infant who suffered a profound hypotensive episode three days antemortem. Nuclear pyknosis and other histologic changes characteristic of ischemic cell necrosis were found throughout the brain and in the retina's photoreceptor-cell layer. These findings suggest that hypoxic ischemia may produce preferential damage to the photoreceptor-cell layer.