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Updated: May 23, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Synthesis, spectroscopic characteristic of novel fluorescent dyes of pyrazoline compounds
Hai-Ying Wang1, Xiao-Xiao Zhang, Jing-Jing Shi
1Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Xuzhou Normal University, Xuzhou 221116, China. haiying11@163.com
Abstract:
Four novel fluorescence dyes of the pyrazoline were synthesized and fully characterized by means of (1)H, (13)C NMR, and HRMS. The optical, electrochemical properties were also investigated. Solvent effect on the fluorescence characteristics of the four compounds indicates that the emission wavelength was red-shifted with the increase of solvent polarity. As we expected, the results indicated that these compounds exhibited high quantum yields. Quantum chemical calculations were used to obtain optimized ground-state geometry, spatial distributions of the HOMO, LUMO levels of the compounds.
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