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Updated: May 23, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
Published on: February 27, 2026
Pneumonectomy for non-small cell lung cancer
Yoshinobu Ichiki1, Akira Nagashima, Yasuhiro Chikaishi
1Department of Chest Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-ku, Kitakyushu, 802-0077, Japan. y-ichiki@med.uoeh-u.ac.jp
Pneumonectomy for non-small cell lung cancer (NSCLC) has acceptable mortality and morbidity. However, advanced stage (III+), T3+, or N2+ disease requires careful patient selection for this major lung cancer surgery.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonology
Background:
- Pneumonectomy is a significant surgical procedure for non-small cell lung cancer (NSCLC).
- Assessing outcomes and identifying prognostic factors is crucial for optimizing patient care.
Purpose of the Study:
- To evaluate the mortality, complications, and major morbidity associated with pneumonectomy for NSCLC.
- To determine the significance of prognostic factors influencing outcomes after pneumonectomy.
Main Methods:
- Retrospective review of 71 patients undergoing pneumonectomy for NSCLC (1992-2007).
- Patients categorized into early (1992-1999) and late (2000-2007) treatment periods.
- Analysis of risk factors for adverse outcomes.
Main Results:
- 30-day and in-hospital mortality rates were 4.2%.
- Overall complication rate was 31.3% with a 5-year survival of 23.1%.
- Advanced pathological stage (III+), T3+, and N2+ disease were significant risk factors for adverse outcomes. Improved survival noted in the later period.
Conclusions:
- Pneumonectomy demonstrates acceptable morbidity and mortality for NSCLC.
- Patients with advanced disease (pathological stage III+, T3+, N2+) require careful consideration.
- Pneumonectomy should be reserved for carefully selected NSCLC patients.
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