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Benign intracranial hypertension after ciprofloxacin administration
1Department of Paediatrics, Watford General Hospital, Herts.
Archives of Disease in Childhood
|October 1, 1990
Insights
Ciprofloxacin, an antibiotic, may cause benign intracranial hypertension in teenagers with cystic fibrosis. This condition, also known as pseudotumor cerebri, requires careful monitoring in patients using this medication.
Area of Science:
- Pharmacology
- Neurology
- Pediatrics
Background:
- Benign intracranial hypertension (BIH) is a neurological condition associated with various medications.
- Antibiotics are among the drug classes that have been linked to the development of BIH.
Observation:
- A teenager diagnosed with cystic fibrosis developed symptoms of BIH.
- The patient had recently been treated with ciprofloxacin, a fluoroquinolone antibiotic.
Findings:
- The temporal association suggests a potential causal link between ciprofloxacin use and the onset of BIH in this patient.
- This case highlights a possible adverse drug reaction to ciprofloxacin.
Implications:
- Clinicians should consider BIH in patients, particularly those with cystic fibrosis, presenting with relevant symptoms during or after ciprofloxacin treatment.
- Further investigation into the association between fluoroquinolone antibiotics and BIH may be warranted to inform clinical practice and patient safety guidelines.
Abstract:
Many drugs, including antibiotics, have been implicated in the aetiology of benign intracranial hypertension. We report the development of benign intracranial hypertension after the use of ciprofloxacin in a teenager with cystic fibrosis.
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