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Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
A case of pemphigus herpetiformis occurring in a 9-year-old boy
Laurel A Leithauser1, Diya F Mutasim
1Department of Dermatology, University of Cincinnati, Cincinnati, Ohio.
Pediatric Dermatology
|April 11, 2012
Abstract:
Pemphigus herpetiformis (PH) is a rare autoimmune vesiculobullous disease. It clinically mimics dermatitis herpetiformis and has immunofluorescent findings typical of pemphigus. PH occurs in adults more commonly than children and is often effectively treated with dapsone. We report a case of PH occurring in a 9-year-old boy that was refractory to dapsone and to various other steroid-sparing medications but resolved with methotrexate.
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