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Related Concept Videos

Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Pedigree Analysis01:35

Pedigree Analysis

Overview
Pedigree Analysis01:35

Pedigree Analysis

Overview
Trihybrid Crosses02:27

Trihybrid Crosses

Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal chance to...
Monohybrid Crosses01:20

Monohybrid Crosses

Overview
Monohybrid Crosses01:20

Monohybrid Crosses

Overview

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Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi
06:44

Induction and Evaluation of Inbreeding Crosses Using the Ant, Vollenhovia Emeryi

Published on: October 5, 2018

Inbreeding in the Thoroughbred horse.

M M Binns1, D A Boehler, E Bailey

  • 1Equine Analysis, Midway, KY 40347, USA. mbinns@equineanalysis.com

Animal Genetics
|April 11, 2012
PubMed
Summary
This summary is machine-generated.

Inbreeding in Thoroughbred horses has significantly increased over the last 40 years. This rise, particularly after 1996, correlates with stallions covering more mares.

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Area of Science:

  • Animal Genetics
  • Population Genetics
  • Equine Science

Background:

  • The Thoroughbred horse industry relies on genetic diversity for breeding.
  • Understanding inbreeding trends is crucial for maintaining breed health and performance.

Purpose of the Study:

  • To investigate changes in the inbreeding coefficient (F) in Thoroughbred horses over the past 45 years.
  • To determine the correlation between birth year and inbreeding levels in the breed.

Main Methods:

  • Genotyping of 467 Thoroughbred horses born between 1961 and 2006.
  • Utilizing the Illumina Equine SNP50 bead chip with 54,602 single nucleotide polymorphisms (SNPs).
  • Estimating the Spearman rank correlation coefficient (r) between birth year and inbreeding coefficients.

Main Results:

  • Inbreeding in Thoroughbreds has increased over the past 40 years.
  • A significant, though weak, positive correlation (r = 0.24, P < 0.001) was found between birth year and inbreeding.
  • The majority of inbreeding increase occurred post-1996, coinciding with increased stallion usage.

Conclusions:

  • Inbreeding in Thoroughbred horses is a growing concern.
  • The trend suggests a potential impact of modern breeding practices, such as increased stallion coverage, on genetic diversity.
  • Further research is warranted to explore the long-term implications for the breed.