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Related Experiment Video

Updated: May 23, 2026

Experimental Protocol for Manipulating Plant-induced Soil Heterogeneity

Experimental Protocol for Manipulating Plant-induced Soil Heterogeneity

Published on: March 13, 2014

Patch testing with constituents of Compositae mixes.

Evy Paulsen¹, Klaus E Andersen

¹Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, DK-5000 Odense C, Denmark. evy.paulsen@ouh.regionsyddanmark.dk

Contact Dermatitis

|April 11, 2012

Summary

This summary is machine-generated.

Parthenolide and Compositae plant extracts are key in diagnosing Compositae contact allergy. Testing with local plant extracts is crucial due to geographical variations and unknown allergens.

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Last Updated: May 23, 2026

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Published on: March 13, 2014

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Area of Science:

Dermatology
Allergology
Plant-based medicine

Background:

Compositae plant extracts aid in diagnosing contact allergy.
Existing European plant mixes have not met ideal diagnostic criteria.

Purpose of the Study:

To identify the most effective screening agents within two commercial Compositae mixes.
To assess the diagnostic utility of specific Compositae constituents.

Main Methods:

76 patients positive to Compositae mix 6% and 29 to Compositae mix 5% were patch tested.
Patients were tested with individual constituents of their respective Compositae mixes.

Main Results:

Parthenolide and parthenolide-containing extracts were the most common positive findings.
German chamomile, yarrow, and arnica also showed positive reactions.
Reactions to German chamomile suggest cross-reactions or unknown allergens; no reactions to Roman chamomile were observed.

Conclusions:

Parthenolide shows promise as a supplement to standard allergy testing series.
Patch testing with local or native plant extracts is recommended.
Geographical variation, unknown allergens in preparations, and individual patient factors necessitate localized testing.