[Necrotizing fasciitis caused by Salmonella Enteritidis]

Area of Science:

• Infectious Diseases
• Microbiology
• Clinical Medicine

Background:

• Necrotising fasciitis and septic shock are life-threatening conditions often requiring intensive care.
• Salmonella Enteritidis is a common cause of gastroenteritis, but extraintestinal manifestations are less frequent.
• Immunocompromised individuals are at higher risk for severe bacterial infections.

Observation:

• A 73-year-old immunocompromised male presented with necrotising fasciitis and septic shock.
• Initial cultures identified Salmonella Enteritidis, treated with a 14-day antibiotic course.
• The patient experienced a relapse of fever and positive blood cultures for Salmonella Enteritidis weeks later.

Findings:

• This case highlights a rare extraintestinal manifestation of Salmonella Enteritidis infection.
• Recurrent Salmonella Enteritidis bacteremia occurred despite initial appropriate antibiotic treatment.
• The patient's immunocompromised status likely contributed to the infection's severity and relapse.

Implications:

• Extended antibiotic therapy may be necessary for immunocompromised patients with extraintestinal Salmonella Enteritidis infections to prevent relapse.
• Clinicians should consider prolonged treatment for Salmonella Enteritidis relapses, especially in vulnerable populations.
• Further research into the long-term management of extraintestinal Salmonella infections is warranted.