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Polymer pen lithography (PPL)-induced site-specific click chemistry for the formation of functional glycan arrays
Shudan Bian1, Jiajun He, Kevin B Schesing
1Department of Chemistry and The Molecular Design Institute, New York University, 100 Washington Square East, New York, NY 10003, USA.
Small (Weinheim an Der Bergstrasse, Germany)
|April 11, 2012
Abstract:
Polymer pen lithography (PPL) can be combined with the Cu(I) -catalyzed azide-alkyne click reaction to create molecular arrays with control over orientation and sub-1 μm feature sizes over cm(2) areas. The process has been applied to the deposition of carbohydrates to form functional glycochips.
