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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

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Related Experiment Video

Updated: May 23, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

Published on: October 26, 2017

New testing for lung cancer screening.

Nichole T Tanner1, Hiren Mehta, Gerard A Silvestri

  • 1Medical University of South Carolina, Charleston, South Carolina, USA. tripici@musc.edu

Oncology (Williston Park, N.Y.)
|April 12, 2012
PubMed
Summary
This summary is machine-generated.

Early lung cancer detection through screening can improve survival rates. New methods like breath analysis and biomarkers show promise for future lung cancer screening strategies.

Related Experiment Videos

Last Updated: May 23, 2026

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening

Published on: October 26, 2017

Area of Science:

  • Oncology
  • Pulmonology
  • Medical Diagnostics

Background:

  • Lung cancer is a leading cause of cancer death globally, often diagnosed at advanced stages with poor prognosis.
  • Early-stage diagnosis and treatment significantly improve patient outcomes, with Stage I lung cancer having a 5-year survival rate near 75%.
  • Effective lung cancer screening aims to detect disease early for surgical cure and reduce unnecessary procedures in healthy individuals.

Purpose of the Study:

  • To review the current landscape of lung cancer screening.
  • To discuss the limitations of generalizing existing screening trial results to the broader community.
  • To highlight emerging diagnostic techniques for lung cancer screening.

Main Methods:

  • Review of existing literature on lung cancer screening.
  • Analysis of the National Lung Cancer Screening Trial (NLST) findings.
  • Evaluation of novel biomarkers and testing modalities.

Main Results:

  • The National Lung Cancer Screening Trial demonstrated that low-dose CT scanning reduces lung cancer mortality in high-risk individuals.
  • Generalizing NLST results to the community presents challenges.
  • Emerging techniques like volatile organic compound analysis, gene expression biomarkers, and serum antibody detection are under investigation.

Conclusions:

  • Low-dose CT screening significantly reduces lung cancer mortality but faces implementation challenges.
  • New diagnostic technologies hold potential for future lung cancer screening algorithms.
  • Further research is needed to validate novel screening methods for widespread clinical use.