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Updated: May 23, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Surgical ablation for atrial fibrillation
Nikolaos Fragakis1, Ioannis Pantos, Jenan Younis
1Department of Cardiology, Hippokration Hospital, Aristotle University Medical School, Thessaloniki, Greece.
Insights
Surgical ablation effectively treats atrial fibrillation (AF) during heart surgery. Minimally invasive techniques show promise for AF patients without other cardiac conditions, but require more research.
Area of Science:
- Cardiovascular Surgery
- Cardiac Electrophysiology
Background:
- Review of historical and current surgical procedures for atrial fibrillation (AF) eradication.
- Evaluation of Cox-Maze procedure limitations, including cardiopulmonary bypass requirement.
- Assessment of concomitant ablation techniques during cardiac surgery for structural heart disease.
Observation:
- Concomitant ablation is safe and effective for AF in mitral valve disease, particularly non-rheumatic.
- Minimally invasive epicardial ablation on a beating heart shows promising initial results.
- Techniques include pulmonary vein isolation, ganglionated plexi ablation, and left atrial lines.
Findings:
- Surgical ablation efficacy is proven, but complex procedures like Cox-Maze are challenging for isolated AF.
- Minimally invasive approaches offer potential benefits but need further clinical validation.
- Optimal techniques, energy sources, and risk-benefit profiles for isolated AF ablation are under investigation.
Implications:
- Surgical ablation is evolving, with minimally invasive options expanding treatment possibilities.
- Further research is crucial to define the role of surgical ablation in managing atrial fibrillation.
- The study highlights the need for tailored approaches based on patient condition and surgical indication.
Abstract:
This paper reviews the history of surgical procedures developed for eradication of atrial fibrillation (AF) during cardiac surgery for structural heart disease, and in patients with AF without other indication for cardiac surgery. Current evidence indicates that, despite their proven efficacy, the Cox-Maze procedure and its modifications require cardiopulmonary bypass and cannot be easily justified in the case of AF without other indication for cardiac surgery. In patients undergoing cardiac surgery for mitral valve disease, concomitant ablation techniques using modifications of the Maze and alternative energy sources appear to be safe and effective in treating AF, especially in non-rheumatic disease. Minimally invasive epicardial ablation has been recently developed and can be performed on a beating heart through small access incision ports. Various techniques combining pulmonary vein isolation, ganglionated plexi ablation, and left atrial lines have been tried. Initial results are promising but further clinical experience is required to establish ideal lesion sets, appropriate energy sources, and the benefit-risk ratio of such an approach in patients without other indication for cardiac surgery. The role of surgical ablation in the current management of AF is under investigation.
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