Related Experiment Video

Updated: May 23, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

Published on: September 15, 2023

[Risk factors for excessive bleeding in patients undergoing open heart surgery with cardiopulmonary bypass]

Cong-yu Shen1, Jin-ning Zhao, Tai-di Zhong

  • 1Department of Anesthesiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University Institute of Clinical Medicine, Hangzhou 310016, China.

Zhonghua Yi Xue Za Zhi
|April 12, 2012
PubMed

Insights

Older age, prior sternotomy, low hematocrit, and longer cardiopulmonary bypass (CPB) duration increase bleeding risk in open heart surgery patients. Identifying these factors aids in managing excessive bleeding during cardiac procedures.

Area of Science:

  • Cardiovascular Surgery
  • Anesthesiology
  • Hematology

Context:

  • Open heart surgery with cardiopulmonary bypass (CPB) carries a risk of excessive perioperative bleeding.
  • Understanding predictors of bleeding is crucial for patient safety and resource management.

Purpose:

  • To identify pre- and intraoperative risk factors for excessive bleeding in adult patients undergoing open heart surgery with CPB.
  • To analyze the relationship between various patient and procedural characteristics and the occurrence of excessive bleeding.

Summary:

  • A retrospective analysis of 1079 patients identified key risk factors for excessive bleeding.
  • Significant predictors included age (≥ 65 years), previous sternotomy, preoperative hematocrit, CPB duration (≥ 120 minutes), and procedure complexity.
  • Excessive bleeding occurred in 11.1% of patients.

Impact:

  • Findings can inform clinical decision-making to mitigate bleeding risks.
  • Improved risk stratification may lead to tailored anesthetic and surgical management strategies.
  • Potential for reduced transfusion requirements and improved patient outcomes in cardiac surgery.
Abstract

More Related Videos

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats09:54

A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats

Published on: March 23, 2018

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...