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A Protocol to Acquire the Degenerative Tenocyte from Humans

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Risk factors in lateral epicondylitis (tennis elbow): a case-control study.

A G Titchener¹, A Fakis, A A Tambe

¹Department of Trauma and Orthopaedics, Royal Derby Hospital, Derby, UK. andytitch@gmail.com

The Journal of Hand Surgery, European Volume

|April 12, 2012

Summary

Lateral epicondylitis risk factors include rotator cuff pathology and De Quervain's disease. Previous smoking history and oral corticosteroid therapy also increase risk for this common elbow condition.

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Area of Science:

Orthopedics
Epidemiology
Rheumatology

Background:

Lateral epicondylitis, commonly known as tennis elbow, is a frequent condition with incompletely understood causes.
Identifying etiological factors and risk associations is crucial for effective prevention and treatment strategies.

Purpose of the Study:

To investigate and quantify constitutional and environmental risk factors associated with lateral epicondylitis.
To assess the relative contributions of various factors in a large community-based cohort.

Main Methods:

A large-scale case-control study was conducted using The Health Improvement Network (THIN) database.
4998 patients diagnosed with lateral epicondylitis were individually matched with controls based on age, sex, and general practice.

Main Results:

Multivariate analysis identified significant risk factors: rotator cuff pathology (OR 4.95), De Quervain's disease (OR 2.48), carpal tunnel syndrome (OR 1.50), oral corticosteroid therapy (OR 1.68), and prior smoking history (OR 1.20).
Factors such as diabetes mellitus, current smoking, trigger finger, rheumatoid arthritis, alcohol intake, and obesity were not significantly associated with lateral epicondylitis.

Conclusions:

Specific musculoskeletal conditions and certain therapies are linked to an increased risk of developing lateral epicondylitis.
This study provides valuable insights into the multifactorial etiology of lateral epicondylitis, aiding in risk stratification and targeted interventions.