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Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation

Demian Obregon1, Huayan Hou, Juan Deng

  • 1Rashid Laboratory for Developmental Neurobiology, Silver Child Development Center, Department of Psychiatry & Behavioral Neuroscience, Morsani College of Medicine, University of South Florida, Tampa 33613, Florida, USA.

Nature Communications
|April 12, 2012
PubMed

Keywords:
amyloidogenic processingBACE1 inhibitionneurodegeneration mechanismsprotein-protein interaction

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