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Time is of the essence: microRNAs and age-associated neurodegeneration
1Institute of Molecular and Cell Biology, 61 Biopolis Dr., Singapore 138673.
Cell Research
|April 12, 2012
Abstract:
Aging is a key risk factor in neurodegenerative disease; however, little is known about cellular pathways that mediate age-associated degeneration of the brain. The Bonini lab has identified a conserved microRNA, miR-34, that plays a neuroprotective role in the aging Drosophila brain and suggests that it functions in temporal control of gene expression.
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